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. 2018 Mar 8;54(21):2635-2638.
doi: 10.1039/c8cc00256h.

Red fluorescent probes for real-time imaging of the cell cycle by dynamic monitoring of the nucleolus and chromosome

Kang-Nan Wang  1 , Xi-Juan Chao, Bing Liu, Dan-Jie Zhou, Liang He, Xiao-Hui Zheng, Qian Cao, Cai-Ping Tan, Chen Zhang, Zong-Wan Mao
Affiliations

Red fluorescent probes for real-time imaging of the cell cycle by dynamic monitoring of the nucleolus and chromosome

Kang-Nan Wang et al. Chem Commun (Camb). .

Abstract

Two cationic molecular rotors, 1 and 2, capable of real-time cell-cycle imaging by specifically dynamic monitoring of nucleolus and chromosome changes were developed. A further study shows that fluorescence enhancements in the nucleolus and chromosome are attributed to a combination effect of interaction with nucleic acid and high condensation of the nucleolus and chromosome.

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