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. 1986 Oct;8(3):243-9.
doi: 10.1016/0143-4179(86)90051-x.

Coexistence of atrial natriuretic factor (ANF) and oxytocin in neurons of the rat hypothalamus

G F Jirikowski, H Back, W G Forssmann, W E Stumpf

Coexistence of atrial natriuretic factor (ANF) and oxytocin in neurons of the rat hypothalamus

G F Jirikowski et al. Neuropeptides. 1986 Oct.

Abstract

Sections of rat hypothalamus were examined immunocytochemically for coexistence of atrial natriuretic factor (cardiodilatin) and oxytocin. These biosynthetically unrelated neuropeptides were demonstrated using the peroxidase-antiperoxidase method followed by immunofluorescence. Neurons immunoreactive for atrial natriuretic factor were found in the supraoptic, periventricular and paraventricular nuclei. A sub-population of these neurons contained oxytocin-like immunoreactivity. They constitute only a small portion of the total number of oxytocinergic neurons.

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