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Case Reports
. 2018 Feb 25;71(2):94-97.
doi: 10.4166/kjg.2018.71.2.94.

Mushroom Poisoning by Macrolepiota neomastoidea

So Yeon Kim  1 , Yang Hyun Baek  1 , Sang Young Han  1 , Sung Wook Lee  1 , Young Hoon Roh  2 , Kwan Woo Kim  2 , Sung Hwa Kang  2 , Jin Sook Jeong  3
Affiliations
Case Reports

Mushroom Poisoning by Macrolepiota neomastoidea

So Yeon Kim et al. Korean J Gastroenterol. .

Abstract

There are currently over 5,000-known species of mushrooms worldwide. Only 20-25% of mushrooms have been named, and 3% of these are poisonous. More than 95% of mushroom poisoning cases occur due to difficulties associated with the identification of mushroom species. Most of the fatal mushroom poisoning cases recorded to date have been related to the Amanita species. Until now, a case of fatal poisoning caused by Macrolepiota neomastoidea (M. neomastoidea) has not been reported in Asia. A 57-year-old male patient was admitted to the emergency room with nausea, vomiting, diarrhea, and abdominal pain. He reported ingesting wild mushrooms with his mother and sister about 2 days ago. His mother and sister were treated with only supportive care, but he was admitted to the intensive care unit and underwent liver transplantation due to acute liver failure. We are reporting a case of fatal M. neomastoidea intoxication from wild mushrooms, a rare case of mushroom poisoning.

Keywords: Acute liver failure; Macrolepiotin; Mushrooms; Poisoning.

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Conflict of interest statement

Conflict of interest: None.

Figures

Fig. 1
Fig. 1
(A) Macrolepiota procera. (B) Macrolepiota neomastoidea.
Fig. 2
Fig. 2
Gross findings. Liver shows reddish-green discoloration by diffuse cholestasis. The weight is approximately 930 g, which is lesser than that of normal liver.
Fig. 3
Fig. 3
Histopathologic findings. (A) Massive hepatocellular necrosis is present in hepatocytes. Residual viable hepatocytes show moderate macrovesicular steatosis (H&E, ×20). (B) Bile ductular proliferation (black arrows) is distinctively observed (Immunohistochemistry with anti-cytokeratin18, ×20). (C, D) There is diffuse and remarkable lobular and porto-periportal inflammation (H&E, ×100).
See this image and copyright information in PMC

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