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Comment
. 2018 Apr;14(4):196.
doi: 10.1038/nrneurol.2018.22. Epub 2018 Feb 23.

Neurodegenerative disease: C9orf72 insufficiency cooperates with toxic repeat peptides to kill neurons

Comment

Neurodegenerative disease: C9orf72 insufficiency cooperates with toxic repeat peptides to kill neurons

Charlotte Ridler. Nat Rev Neurol. 2018 Apr.
No abstract available

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  • Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
    Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK. Shi Y, et al. Nat Med. 2018 Mar;24(3):313-325. doi: 10.1038/nm.4490. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400714 Free PMC article.

References

    1. Nat Med. 2018 Mar;24(3):313-325 - PubMed

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