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. 2018 Feb;15(2):226-229.
doi: 10.30773/pi.2017.06.05. Epub 2017 Dec 14.

A Neuroleptic Malignant Syndrome Without Rigidity

Affiliations

A Neuroleptic Malignant Syndrome Without Rigidity

İlker Özdemir et al. Psychiatry Investig. 2018 Feb.

Abstract

Neuroleptic malignant syndrome (NMS) is an uncommon but potentially lethal idiosyncratic reaction which may emerge in the aftermath of the treatments with neuroleptics demonstrating itself with the symptoms of altered consciousness, high fever, impaired autonomic functions, and muscle rigidity. Although various risk factors have been identified for NMS, its etiology is not completely known. The mortality and morbidity related with NMS could be reduced by early diagnosis, interruption of the neuroleptics used within a short period and aggressive treatment. Our case is different from general NMS cases due to lack of rigidity. A NMS case which developed within a short time in the aftermath of multiple antipsychotic use and wherein no rigidity was observed shall be discussed in this case report.

Keywords: Antipsychotic agents; Muscular rigidity; Neuroleptic malignant syndrome.

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References

    1. Nielsen J, Bruhn AM. Atypical neuroleptic malignant syndrome caused by olanzapine. Acta Psychiatr Scand. 2005;112:238–240. - PubMed
    1. Semiz ÜB. Neuroleptic Malignant Syndrome. In: Ceylan ME, Çetin M, editors. Schizophrenia. 4th Edition. Istanbul: İncekara Matbaacılık; 2009. pp. 167–176.
    1. Tural Ü, Önder E. Clinical and pharmacologic risk factors for neuroleptic malignant syndrome and their association with death. Psychiatry Clin Neurosci. 2010;64:79–87. - PubMed
    1. Sarkar P, Natarajan C, Gode N. Prevalence of neuroleptic malignant syndrome in 672 consecutive male in patients. Indian J Psychiatry. 2009;51:202–205. - PMC - PubMed
    1. Chandran GJ, Mikler JR, Keegan DL. Neuroleptic malignant syndrome: case report and discussion. CMAJ. 2003;169:439–442. - PMC - PubMed

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