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Case Reports
. 2018 Mar;34(3):342.e13-342.e15.
doi: 10.1016/j.cjca.2017.12.017. Epub 2017 Dec 27.

Multiple Thromboembolic Events from a Left Atrial Appendage Occlusion Device

Graeme Prosperi-Porta  1 , Gregory Schnell  2 , Jillian Colbert  2 , Angela Franko  3 , Stephen B Wilton  2 , Vikas P Kuriachan  4
Affiliations
Case Reports

Multiple Thromboembolic Events from a Left Atrial Appendage Occlusion Device

Graeme Prosperi-Porta et al. Can J Cardiol. 2018 Mar.

Abstract

Left atrial appendage occlusion devices are an alternative to oral anticoagulation in patients with nonvalvular atrial fibrillation who are at risk of ischemic stroke. Thromboprophylaxis after implantation is recommended, but the optimal regimen is unknown. We report a clinicopathologic case in which thrombus adherent to an incompletely endothelialized WATCHMAN device (Boston Scientific, Marlborough, MA) resulted in multiple thromboembolic events, contributing to a fatal outcome. This case illustrates uncertainties regarding the device's endothelialization process.

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