The BEIR VII Estimates of Low-Dose Radiation Health Risks Are Based on Faulty Assumptions and Data Analyses: A Call for Reassessment
- PMID: 29475999
- DOI: 10.2967/jnumed.117.206219
The BEIR VII Estimates of Low-Dose Radiation Health Risks Are Based on Faulty Assumptions and Data Analyses: A Call for Reassessment
Abstract
The 2006 National Academy of Sciences Biologic Effects of Ionizing Radiation (BEIR) VII report is a well-recognized and frequently cited source on the legitimacy of the linear no-threshold (LNT) model-a model entailing a linear and causal relationship between ionizing radiation and human cancer risk. Linearity means that all radiation causes cancer and explicitly excludes a threshold below which radiogenic cancer risk disappears. However, the BEIR VII committee has erred in the interpretation of its selected literature; specifically, the in vitro data quoted fail to support LNT. Moreover, in vitro data cannot be considered as definitive proof of cancer development in intact organisms. This review is presented to stimulate a critical reevaluation by a BEIR VIII committee to reassess the validity, and use, of LNT and its derived policies.
Keywords: BEIR VII; linear no-threshold; radiological imaging.
© 2018 by the Society of Nuclear Medicine and Molecular Imaging.
Comment in
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Radiation Dose Does Indeed Matter: Proof That Invalidates The Linear No-Threshold Model.J Nucl Med. 2018 Nov;59(11):1779-1780. doi: 10.2967/jnumed.118.217950. Epub 2018 Aug 10. J Nucl Med. 2018. PMID: 30097506 No abstract available.
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