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. 2019 Sep;5(5):849-852.
doi: 10.1016/j.euf.2018.02.005. Epub 2018 Feb 21.

Adjuvant recMAGE-A3 Immunotherapy After Cystectomy for Muscle-invasive Bladder Cancer: Lessons Learned from the Phase 2 MAGNOLIA Clinical Trial

Peter F A Mulders  1 , Luis Martínez-Piñeiro  2 , Axel Heidenreich  3 , Marko Babjuk  4 , Marc Colombel  5 , Renzo Colombo  6 , Piotr Radziszewski  7 , Igor Korneyev  8 , Cristian Surcel  9 , Pavel Yakovlev  10 , J Alfred Witjes  1 , Christien Caris  11 , Raymond Schipper  11 , Wim P J Witjes  12 ; MAGNOLIA Study Group of the EAU Research Foundation
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Adjuvant recMAGE-A3 Immunotherapy After Cystectomy for Muscle-invasive Bladder Cancer: Lessons Learned from the Phase 2 MAGNOLIA Clinical Trial

Peter F A Mulders et al. Eur Urol Focus. 2019 Sep.

Abstract

The MAGNOLIA study, investigating the concept of perioperative immunotherapy in muscle- invasive bladder cancer, was prematurely terminated. The lessons learned that should be considered before initiating and conducting future clinical trials in this field are highlighted.

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