Review
doi: 10.1016/j.biopha.2018.02.050.
Epub 2018 Feb 23.
Angiogenic potential of YKL-40 in the dynamics of tumor niche
Affiliations
- PMID: 29477911
- DOI: 10.1016/j.biopha.2018.02.050
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Review
Angiogenic potential of YKL-40 in the dynamics of tumor niche
Biomed Pharmacother.
2018 Apr.
Abstract
A multitude of clinical studies showed the elevation of YKL-40 in subjects with different kinds of tumors. It is predicted that an inherent correlation exists between survivals of cancer patients with total YKL-40 serum levels, making this factor as a potential novel biomarker. However, the crucial role of YKL-40 in the dynamics of cancers, especially angiogenesis, has not yet been completely addressed. In this review, we highlighted the various facets of YKL-40 and its importance in cancer biology as a bio-shuttle in gene therapy.
Keywords: Angiogenesis; Cancer biology; Keyword; YKL-40 factor.
Copyright © 2018 Elsevier Masson SAS. All rights reserved.
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