Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Feb 13;2018(2):rjy012.
doi: 10.1093/jscr/rjy012. eCollection 2018 Feb.

Solitary pancreatic head metastasis from tibial adamantinoma: a rare indication to pancreaticoduodenectomy

S Silvestri  1 , G Deiro  2 , S Sandrucci  3 , A Comandone  4 , L Molinaro  5 , L Chiusa  5 , G R Fronda  6 , A Franchello  7
Affiliations
Case Reports

Solitary pancreatic head metastasis from tibial adamantinoma: a rare indication to pancreaticoduodenectomy

S Silvestri et al. J Surg Case Rep. .

Abstract

Pancreatic metastases are rare, <2% of all pancreatic neoplasia. This is the first case of pancreatic metastasis from adamantinoma, a rare, low grade and slow growing tumor which is frequently localized in long bones. We describe a case of a 45-year-old woman presenting with increased bilirubin level. Computed tomography and ecoendoscopic ultra sonography revealed a pancreatic head mass. Fine-needle aspiration biopsy was consistent with metastatic adamantinoma. The patient was submitted to a standard pancreaticoduodenectomy. As in the case presented, standard pancreatic resections are safe and feasible options to treat non-pancreatic primary tumor improving patient's survival and quality of life.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
MDCT scan. (A) CT scan with well-defined hypodense pancreatic head mass of 2 cm of diameter after contrast medium intravenous injection. (B) CT scan which highlight bile duct dilatation.
Figure 2:
Figure 2:
EUS. EUS confirmed the presence of a hypoechoic and well-defined mass of diameter 18 × 15 mm.
Figure 3:
Figure 3:
Immunohistochemical staining. (A) Hematoxylin and eosin stain (H&E stain). (BandC) H&E stain with magnification 4× and 20×. (D) Anti-cytokeratin AE1/AE3 + (5×). (E) Vimentine + (4×). (F) ActineML + (4×). (G) CD99 + weak (10×). (H) CD117 − (2×). (I) Desmin – (4×).
See this image and copyright information in PMC

References

    1. Kitsoulis P, Charchanti A, Paraskevas G, Marini A, Karatzias G. Adamantinoma. Acta Orthop Belg 2007;73:425–31. - PubMed
    1. Roque P, Mankin HJ, Rosenberg A. Adamantinoma: an unusual bone tumour. Chir Organi Mov 2008;92:149–54. - PubMed
    1. Szendroi M, Antal I, Arató G. Adamantinoma of long bones: a long-term follow-up study of 11 cases. Pathol Oncol Res POR 2009;15:209–16. - PubMed
    1. Silvestri S, Franchello A, Deiro G, Galletti R, Cassine D, Campra D, et al. . Preoperative oral immunonutrition versus standard preoperative oral diet in well nourished patients undergoing pancreaticoduodenectomy. Int J Surg Lond Engl 2016;31:93–9. - PubMed
    1. Papagelopoulos PJ, Mavrogenis AF, Galanis EC, Savvidou OD, Inwards CY, Sim FH. Clinicopathological features, diagnosis, and treatment of adamantinoma of the long bones. Orthopedics 2007;30:211–5. quiz 216–7. - PubMed

Publication types