Development and experimental application of contact probe catheter for laser angioplasty

Abstract

A sapphire contact probe laser catheter was developed to increase the dimensions of tunnels created by laser angioplasty. The device consisted of a round sapphire probe (2.2 mm diameter) attached to an 8F catheter into which a 0.2 mm optical fiber was inserted with a tip maintained at 3 mm from the sapphire. The fiber was connected to a continuous wave neodymium yttrium aluminum garnet (Nd-YAG) laser. A saline perfusate was circulated through the catheter during laser emissions to prevent excessive heating of the fiber tip. The system was used in vitro on 16 sections of atherosclerotic calcified human cadaver aortic walls, using diluted blood as a medium, at powers ranging from 10 to 40 W and exposure times from 1 to 4 seconds. Six craters were created at each energy level. The system was also used on six human cadaver, agar-embedded, obstructed iliac and femoral arteries, using 40 W and 2 second laser emissions. Dimensions of probe-created craters were compared with those obtained using bare fibers. The shape of the probe craters was that of a truncated cone with the entry hole wider than the exit, as opposed to the cylindrical shape created with unmodified bare fibers. At 120 J (seconds X watts), areas of entry and exit probe-formed holes were greater than those created with the bare fibers (6.7 +/- 0.5 and 3.4 +/- 0.6 versus 0.2 +/- 0.01 mm2, respectively, p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)