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. 1978 Jul;22(4):343-51.

Methodical aspects of the experimental chemotherapy of viral infections

  • PMID: 29480

Methodical aspects of the experimental chemotherapy of viral infections

A S Galabov et al. Acta Virol. 1978 Jul.

Abstract

An analysis of the methods of testing the antiviral activity in vitro (in cell cultures) and in vivo (in experimental virus infections) is presented. The necessity of applying two-stage screening in vitro is emphasized. The chemotherapeutic viral models is in vitro testing as well as the principles of modelling of experimental viral infections are examined. Criteria for stage-by-stage assessment of the antiviral activity of the substances tested are formulated.

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