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. 2018 Mar;66(3):394-399.
doi: 10.4103/ijo.IJO_726_17.

Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery

Parveen Rewri  1 , Madhavi Sharma  1 , D P Vats  1 , Aparna Singhal  1
Affiliations

Seroprevalence, risk associations, and cost analysis of screening for viral infections among patients of cataract surgery

Parveen Rewri et al. Indian J Ophthalmol. 2018 Mar.

Abstract

Purpose: The purpose of this study was to estimate the prevalence of blood-borne viral infections (triple H: HBV-hepatitis B virus, HCV-hepatitis C virus, and HIV-human immunodeficiency virus) among cataract patients, sought possible risk associations and discuss feasibility of universal preoperative screening.

Methods: This prospective, cross-sectional study enrolled consecutive patients of senile cataract. They were screened by immunoassay-based rapid diagnostic card tests for blood-borne viral infections. Positive cases were confirmed with confirmatory ELISA tests. Seropositive patients were enquired about the exposure to possible risk associations for acquiring these infections. Cost of card test per patient was calculated.

Results: The prevalence of seropositivity for triple H viral infections (HBV, HCV, and HIV) among patients of senile cataract was 5.9% (95% confidence interval [CI]: 5.3-6.6), and HCV was most common viral infection. The dental extraction was most common (54%; 95% CI:48-60) possible risk association. The total cost of primary screening per patient for triple H infections(HBV, HCV, and HIV) was $0.93.

Conclusion: The prevalence of blood-borne viral infection among cataract patients is high in this area. Awareness of the prevalence of blood-borne viral infections in service area, along with knowledge of rate of accidental exposure and risk of transmission would help to understand cost-effectiveness of universal preoperative screening before cataract surgery.

Keywords: Cataract; cost-analysis; hepatitis b virus; hepatitis c virus; human immunodeficiency virus; prevalence; screening.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
District or residence area of seropositive patients. (The number below district name shows percentage of seropositive patients. These numbers are relative, as proportions of patients coming for any area for the cataract surgery in this institute vary)
Figure 2
Figure 2
Comparison of the prevalence of viral infections among cataract patients in this study with population-based national data
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