Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Mar;66(3):451-453.
doi: 10.4103/ijo.IJO_852_17.

Isolated neurofibroma of the eyelid mimicking recurrent chalazion

H Vijaya Pai  1 , Surabhi Abbagani  1 , J Padma Priya  2
Affiliations
Case Reports

Isolated neurofibroma of the eyelid mimicking recurrent chalazion

H Vijaya Pai et al. Indian J Ophthalmol. 2018 Mar.

Erratum in

Abstract

Neurofibroma is a peripheral nerve sheath tumor which is seen in neurofibromatosis type 1 and is characterized by various ophthalmic manifestations. Solitary neurofibroma of the eyelid is rare. We report a case of a 53-year-old female patient who presented with a painless swelling in the left upper lid of 4 years' duration. She had undergone surgery for the same lesion twice. The lesion was excised and histopathological examination revealed a solitary neurofibroma. She did not have any other features of generalized neurofibromatosis.

Keywords: Lid tumor; neurofibroma; recurrent chalazion.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Clinical photograph showing a well-circumscribed round swelling in the left eye upper lid
Figure 2
Figure 2
Microscopic section showing bundles of spindle-shaped cells with wavy-to-elongated nuclei, surrounded by fibrocollagenous stromal with entrapped nerve bundle (arrow) along with lymphocytes and plasma cells in (H and E, ×40)
Figure 3
Figure 3
Microscopic section showing mast cell (arrow) interspersed with the tumor cells in (H and E, ×100)
Figure 4
Figure 4
Immunohistochemistry with S-100 marker showing diffuse positivity of tumor cells
Figure 5
Figure 5
Postoperative photograph
See this image and copyright information in PMC

References

    1. Anderson JL, Gutmann DH. Handbook of Clinical Neurology. Vol. 132. United States of America: Elsevier; 2015. Neurofibromatosis type 1; pp. 75–86. - PubMed
    1. Neurofibromatosis. Conference statement. National Institutes of Health consensus development conference. Arch Neurol. 1988;45:575–8. - PubMed
    1. Chen N, Hsu YH, Lee YC. Solitary neurofibroma of eyelid masquerading as chalazion. Int Med Case Rep J. 2017;10:177–9. - PMC - PubMed
    1. Ozdal PC, Codère F, Callejo S, Caissie AL, Burnier MN. Accuracy of the clinical diagnosis of chalazion. Eye (Lond) 2004;18:135–8. - PubMed
    1. Huang YY, Liang WY, Tsai CC, Kao SC, Yu WK, Kau HC, et al. Comparison of the clinical characteristics and outcome of benign and malignant eyelid tumors: An analysis of 4521 eyelid tumors in a tertiary medical center. Biomed Res Int. 2015;2015:453091. - PMC - PubMed

Publication types