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. 2018 Jul;142(1):297-301.e2.
doi: 10.1016/j.jaci.2018.02.008. Epub 2018 Mar 2.

Recurrent wheezing in children following human metapneumovirus infection

Andrea M Coverstone  1 , Brad Wilson  1 , Dana Burgdorf  1 , Kenneth B Schechtman  1 , Gregory A Storch  1 , Michael J Holtzman  1 , Mario Castro  1 , Leonard B Bacharier  1 , Kaharu Sumino  2
Affiliations

Recurrent wheezing in children following human metapneumovirus infection

Andrea M Coverstone et al. J Allergy Clin Immunol. 2018 Jul.

Abstract

We showed that early in life human metapneumovirus infection is associated with increased risk of subsequent wheezing episodes.

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Figures

Figure 1.
Figure 1.
Survival analysis for wheezing and asthma. Kaplan-Meier estimates of freedom from A. any wheezing episodes, p=0.004; B. wheezing episodes with colds, p=0.005; C. wheezing episodes without colds, p=0.003; and D. physician-diagnosed asthma, p=0.14. HMPV LRTI subjects had wheezing earlier in follow-up compared to controls subjects but no significant difference in the time to asthma diagnosis. HMPV, human metapneumovirus; LRTI, lower respiratory tract infection.
Figure 1.
Figure 1.
Survival analysis for wheezing and asthma. Kaplan-Meier estimates of freedom from A. any wheezing episodes, p=0.004; B. wheezing episodes with colds, p=0.005; C. wheezing episodes without colds, p=0.003; and D. physician-diagnosed asthma, p=0.14. HMPV LRTI subjects had wheezing earlier in follow-up compared to controls subjects but no significant difference in the time to asthma diagnosis. HMPV, human metapneumovirus; LRTI, lower respiratory tract infection.
Figure 1.
Figure 1.
Survival analysis for wheezing and asthma. Kaplan-Meier estimates of freedom from A. any wheezing episodes, p=0.004; B. wheezing episodes with colds, p=0.005; C. wheezing episodes without colds, p=0.003; and D. physician-diagnosed asthma, p=0.14. HMPV LRTI subjects had wheezing earlier in follow-up compared to controls subjects but no significant difference in the time to asthma diagnosis. HMPV, human metapneumovirus; LRTI, lower respiratory tract infection.
Figure 1.
Figure 1.
Survival analysis for wheezing and asthma. Kaplan-Meier estimates of freedom from A. any wheezing episodes, p=0.004; B. wheezing episodes with colds, p=0.005; C. wheezing episodes without colds, p=0.003; and D. physician-diagnosed asthma, p=0.14. HMPV LRTI subjects had wheezing earlier in follow-up compared to controls subjects but no significant difference in the time to asthma diagnosis. HMPV, human metapneumovirus; LRTI, lower respiratory tract infection.
eFigure 1.
eFigure 1.
Flow diagram of study recruitment, eligibility and participation. HMPV, human metapneumovirus; LRTI, lower respiratory tract infection.
See this image and copyright information in PMC

References

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