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Meta-Analysis
. 2018 Feb 26;8(1):3640.
doi: 10.1038/s41598-018-21912-x.

Factors influencing intention to obtain the HPV vaccine in South East Asian and Western Pacific regions: A systematic review and meta-analysis

Diviya Santhanes  1 , Che Pui Yong  1 , Yan Ye Yap  1 , Pui San Saw  1 , Nathorn Chaiyakunapruk  1   2   3   4 , Tahir Mehmood Khan  5   6   7
Affiliations
Meta-Analysis

Factors influencing intention to obtain the HPV vaccine in South East Asian and Western Pacific regions: A systematic review and meta-analysis

Diviya Santhanes et al. Sci Rep. .

Abstract

Since licensing in 2006, there has been poor uptake of the HPV vaccine among the targeted population in the South East Asia Region (SEAR) and Western Pacific Region (WPR). A systematic review was conducted to identify the studies exploring the relationship between factors and intention for HPV vaccination among women in SEAR and WPR countries. Nineteen studies were identified as suitable for qualitative synthesis, and three as suitable for meta-analysis. Most women had a positive intention to have an HPV vaccine (range 57%-85%). Having a positive intention to vaccinate was significantly higher among women not aware of HPV infection (OR: 1.34, 95% CI: 1.02-1.76) and HPV vaccine (OR: 1.57, 95% CI: 1.26-1.96). Lower knowledge level and less confidence in safety and efficacy of the vaccine, negatively affected intention to vaccinate. Perceiving the vaccine to be expensive, low perception of contracting HPV infection and cervical cancer, and lack of concrete recommendations from healthcare providers also negatively affected intention to vaccinate. This review suggests the decision-making processes of women in SEAR and WPR is influenced by the cost of vaccination, perceived efficacy and safety of vaccine, provision of information on vaccination, and the awareness about HPV infection and the HPV vaccine.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Flowchart for identification and inclusion of articles in systematic review.
Figure 2
Figure 2
Forest plot of the two studies estimating the effect of awareness of HPV infection on positive intention to have the HPV vaccine.
Figure 3
Figure 3
Forest plot of the three studies estimating the effect of awareness of HPV vaccine on positive intention to have the HPV vaccine.
See this image and copyright information in PMC

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