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. 2018 Jan;44(1):79-81.
doi: 10.5152/tud.2017.39039. Epub 2017 Dec 19.

Giant malignant fibrous histiocytoma of the testis

Volkan Ülker  1 , Hasan Anıl Atalay  1 , Çağlar Çakır  2 , Aytül Sargan  2
Affiliations

Giant malignant fibrous histiocytoma of the testis

Volkan Ülker et al. Turk J Urol. 2018 Jan.

Abstract

We present a case of malignant fibrous histiocytoma of the testis in a 59 year- old male who admitted to our hospital with left testicular painless mass presenting for two months. A scrotal ultrasound examination and magnetic resonance imaging revealed a 9 cm left testicular solid mass. Serum tumor markers were unremarkable. The patient underwent left radical orchiectomy. Histopathologic diagnosis was giant cell variant of malignant fibrous histiocytoma which composed of varying amounts of a mixture of spindled, rounded and osteoclastic type giant cells. Hemorrhagic and necrotic areas were seen between tumor nodules. In immunohystochemical staining, vimentin, CD68 were positive and SMA was focally positive. The patient then received adjuvant chemoterapy and currently, he has no sign of recurrence.

Keywords: Giant cell; malignant fibrous histiocytoma; testicular tumor; testis.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
MR imaging showing left testicular solid mass on sagittal FSE T2 signal MR: magnetic resonance; FSE: fast-spin echo
Figure 2. a–c
Figure 2. a–c
(a) H&E ×100,tumor is composed of mixture of spindled, rounded, and osteoclastic type giant cells in varying amounts, and atypic mitoses can be seen. (b) H&E ×400 pleomorphic and hyperchromatic tumor cells with giant cell. (c) Vimentin ×100
See this image and copyright information in PMC

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