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. 2018 Feb 27;319(8):818-819.
doi: 10.1001/jama.2017.21547.

Gabapentin for Chronic Neuropathic Pain

Andrew Moore  1 , Sheena Derry  1 , Philip Wiffen  1
Affiliations

Gabapentin for Chronic Neuropathic Pain

Andrew Moore et al. JAMA. .

Abstract

Clinical question: Is gabapentin associated with pain relief in people with chronic neuropathic pain?

Bottom line: Oral gabapentin (1200-3600 mg/d for 4-12 weeks) for patients with moderate or severe neuropathic pain from postherpetic neuralgia (PHN) or painful diabetic neuropathy (PDN) is associated with pain reduction of at least 50% in 14% to 17% more patients than placebo.

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