A Fat Lot of Good for Wound Healing
- PMID: 29486189
- DOI: 10.1016/j.devcel.2018.02.009
A Fat Lot of Good for Wound Healing
Abstract
The insect's fat body combines metabolic and immunological functions. In this issue of Developmental Cell, Franz et al. (2018) show that in Drosophila, cells of the fat body are not static, but can actively "swim" toward sites of epithelial injury, where they physically clog the wound and locally secrete antimicrobial peptides.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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Fat Body Cells Are Motile and Actively Migrate to Wounds to Drive Repair and Prevent Infection.Dev Cell. 2018 Feb 26;44(4):460-470.e3. doi: 10.1016/j.devcel.2018.01.026. Dev Cell. 2018. PMID: 29486196 Free PMC article.
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