Meconium Ileus
- PMID: 29487495
- PMCID: PMC5825880
- DOI: 10.1055/s-0037-1609027
Meconium Ileus
Abstract
Cystic fibrosis is one of the most common inheritable traits in Caucasians. Meconium ileus and its potential complications are the most likely reasons that these patients will need surgical care. Surgical intervention is usually needed in the neonatal period but may also be required later in life. This article discusses the various ways cystic fibrosis can affect the gastrointestinal tract. Both the operative and nonoperative management of complicated and uncomplicated meconium ileus are discussed in the neonatal period as well as long-term issues, such as distal intestinal obstructive syndrome, fibrosing colonopathy, and rectal prolapse, all of which may be seen in older children and adults.
Keywords: cystic fibrosis; cystic fibrosis transmembrane conductance regulator; distal intestinal obstruction syndrome; epithelial sodium channels; fibrosing colonopathy; meconium ileus; newborn intestinal obstruction; rectal prolapse.
Figures
References
-
- Wilcken B, Wiley V, Sherry G, Bayliss U. Neonatal screening for cystic fibrosis: a comparison of two strategies for case detection in 1.2 million babies. J Pediatr. 1995;127(06):965–970. - PubMed
-
- Kleven D T, McCudden C R, Willis M S.Cystic fibrosis: newborn screening in America MLO Med Lab Obs 2008400716–18., 22, 24–27 - PubMed
-
- Kopp B T, Nicholson L, Paul G, Tobias J, Ramanathan C, Hayes D., Jr Geographic variations in cystic fibrosis: an analysis of the U.S. CF Foundation Registry. Pediatr Pulmonol. 2015;50(08):754–762. - PubMed
-
- Feuchtbaum L, Carter J, Dowray S, Currier R J, Lorey F. Birth prevalence of disorders detectable through newborn screening by race/ethnicity. Genet Med. 2012;14(11):937–945. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
