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. 2018 Mar 1;18(1):233.
doi: 10.1186/s12885-018-4139-6.

Dairy products and colorectal cancer in middle eastern and north African countries: a systematic review

K El Kinany  1   2 , M Deoula  3 , Z Hatime  3 , B Bennani  4 , K El Rhazi  3
Affiliations

Dairy products and colorectal cancer in middle eastern and north African countries: a systematic review

K El Kinany et al. BMC Cancer. .

Abstract

Background: This systematic review was conducted to explain the association between dairy products and colorectal cancer (CRC) risk in Middle Eastern and North African countries (MENA).

Methods: The database consulted were PubMed, Clinical Trials, and Cochrane to extract the relevant studies published till the 31stof December 2016, using inclusion and exclusion criteria according to Prisma Protocol. The characteristics of these studies comprised the consumption of all types of dairy products in relation to CRC risk.

Results: Seven studies were included in this review. For dairy products overall, no significant association was found. Regarding modern dairy products, included studies found controversial results with OR = 9.88 (95% CI: 3.80-24.65) and ORa = 0.14 (95% CI: 0.02-0.71). A positive association was reported between traditional dairy products and CRC risk, to OR = 18.66 (95% CI: 3.06-113.86) to OR = 24 (95% CI: 1.74-330.82) to ORa = 1.42 (95% CI: 0.62-3.25), ptrend = 0.03. Calcium was inversely associated with the CRC risk with ORa = 0.08 (95% CI: 0.04-0.17).

Conclusion: This is the first systematic review which illustrated the association between dairy consumption and CRC risk in MENA region. The results were inconsistent and not always homogeneous. Further specified studies may be warranted to address the questions about the association between CRC and dairy products in a specific context of MENA region.

Keywords: Colorectal cancer; Dairy products; Middle eastern and north African countries; Prevention; Risk; Systematic review.

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Ethics approval and consent to participate

Ethical approval is not required for this review.

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Not applicable.

Competing interests

The authors declare that they have no competing interests.

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Figures

Fig. 1
Fig. 1
The PRISMA Diagram of the selected papers
See this image and copyright information in PMC

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References

    1. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. A Cancer Journal of Clinicians. 2012;65(2):87–108. doi: 10.3322/caac.21262. - DOI - PubMed
    1. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136(5):359–386. doi: 10.1002/ijc.29210. - DOI - PubMed
    1. International Agency for Research on Cancer: World Cancer Report; 2014.
    1. Belahsen R. Nutrition transition and food sustainability. Proc Nutr Soc. 2014;73(3):385–388. doi: 10.1017/S0029665114000135. - DOI - PubMed
    1. Global Burden of Disease Cancer Collaboration. Fitzmaurice C, Allen C, Barber RM, Barregard L, Bhutta ZA, Brenner H, Dicker DJ, Chimed-Orchir O, Dandona R, et al. Global, regional, and National Cancer Incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study. JAMA Oncology. 2016;3(4):524–548. doi: 10.1001/jamaoncol.2016.5688. - DOI - PMC - PubMed

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