Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Jan;22(Suppl 1):S11-S15.
doi: 10.4103/jomfp.JOMFP_69_15.

Aggressive adenomatoid odontogenic tumor of the mandible: A rare case report and review of the literature

Affiliations
Case Reports

Aggressive adenomatoid odontogenic tumor of the mandible: A rare case report and review of the literature

Sana Shaikh et al. J Oral Maxillofac Pathol. 2018 Jan.

Abstract

Adenomatoid odontogenic tumor (AOT) is a relatively rare and distinct odontogenic tumor that is exclusively odontogenic epithelium in origin. Although considerable numbers of reports are available with regard to the clinical and histological spectrum of AOT, very few have highlighted its rare aggressive nature. This article focuses on an AOT causing jaw swelling in the mandibular anterior region with cortical plate expansion and perforation, root resorption and paresthesia. The present case had remarkably unusual clinical and radiographic features that distinguished it from most conventional AOTs and supported its neoplastic nature.

Keywords: Adenomatoid odontogenic tumor; aggressive; mandible.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Diffuse swelling causing obliteration of labial vestibule with missing permanent mandibular right central incisor
Figure 2
Figure 2
Panoramic radiograph showing impacted permanent mandibular right central incisor in a well-defined radiolucency, expansion and thinning of the inferior border of the mandible, displacement and resorption of the anterior teeth
Figure 3
Figure 3
Cone-beam computerized tomography reveals buccolingual expansion, thinning and erosion of buccal cortical plate
Figure 4
Figure 4
Photomicrograph illustrates a highly cellular tumor mass with multinodular proliferation of spindle, cuboidal, columnar and stellate reticulum-like cells forming nests of rosette-like and duct-like structures (H and E stain, ×10)
Figure 5
Figure 5
Gross appearance revealing a tan colored, roughly spherical-shaped tumor mass with embedded root of mandibular right central incisor

References

    1. Regezi JA, Kerr DA, Courtney RM. Odontogenic tumors: Analysis of 706 cases. J Oral Surg. 1978;36:771–8. - PubMed
    1. Philipsen HP, Reichart PA, Zhang KH, Nikai H, Yu QX. Adenomatoid odontogenic tumor: Biologic profile based on 499 cases. J Oral Pathol Med. 1991;20:149–58. - PubMed
    1. Nomura M, Tanimoto K, Takata T, Shimosato T. Mandibular adenomatoid odontogenic tumor with unusual clinicopathologic features. J Oral Maxillofac Surg. 1992;50:282–5. - PubMed
    1. Yadav JS, Mohindra S, Gupta K. Adenomatoid odontogenic tumor of maxillary sinus. AIJCR. 2011;4:53–6.
    1. Swasdison S, Dhanuthai K, Jainkittivong A, Philipsen HP. Adenomatoid odontogenic tumors: An analysis of 67 cases in a Thai population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105:210–5. - PubMed

Publication types