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Case Reports
. 2018 Feb 22;2018(2):rjy023.
doi: 10.1093/jscr/rjy023. eCollection 2018 Feb.

Primary hyperparathyroidism presenting as acute psychosis secondary to hypercalcaemia requiring curative parathyroidectomy

Prateush Singh  1 , Yehudit Bauernfreund  2 , Pallavi Arya  3 , Esha Singh  3 , Justin Shute  2
Affiliations
Case Reports

Primary hyperparathyroidism presenting as acute psychosis secondary to hypercalcaemia requiring curative parathyroidectomy

Prateush Singh et al. J Surg Case Rep. .

Abstract

Primary hyperparathyroidism (PHPT) can cause hypercalcaemia secondary to a pathologically high secretion of parathyroid hormone. Rarely this can first manifest as acute psychosis. It is imperative to exclude organic causes of psychosis before labelling the psychosis as primarily psychological. If hypercalcaemia is revealed, investigation is required to elucidate the underlying cause whilst instigating treatment to lower serum calcium levels. If PHPT is the underlying pathology, subsequent treatment involves surgical exploration and resection of the parathyroid adenoma or hyperplasia.

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Figures

Figure 1:
Figure 1:
Ultrasound neck image illustrating the parathyroid adenoma measuring 11 mm with echogenicity and internal vasculature.
See this image and copyright information in PMC

References

    1. Tang A, O’Sullivan AJ, Diamond T, Gerard A, Campbell P. Psychiatric symptoms as a clinical presentation of Cushing’s syndrome. Ann Gen Psychiatry 2013;12:23. - PMC - PubMed
    1. Mahmood A, Ashton AK, Hina FH. Psychotic symptoms with underlying graves disease: a case report. Prim Care Companion J Clin Psychiatry 2005;7:311–2. - PMC - PubMed
    1. Heinrich TW, Grahm G. Hypothyroidism presenting as psychosis: myxedema madness revisited. Prim Care Companion J Clin Psychiatry 2003;5:260–6. - PMC - PubMed
    1. Babar G, Alemzadeh R. A case of acute psychosis in an adolescent male. Case Rep Endocrinol 2014;2014:937631. - PMC - PubMed
    1. Athanassenas G, Papadopoulos E, Kourkoubas A. Serum calcium and magnesium levels in chronic schizophrenics. J Clin Psychopharmacol 1983;3:212–6. - PubMed

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