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Book

Anabolic Steroids

Stephen W. Leslie  1 , Sajedur Rahman  2 , Kavitha Ganesan  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Anabolic Steroids

Stephen W. Leslie et al.
Free Books & Documents

Excerpt

Anabolic steroids are synthetic derivatives of testosterone that have both medical applications and a high potential for misuse. These agents play a critical role in managing conditions such as primary hypogonadism, delayed male puberty, hypogonadotropic and idiopathic hypogonadism, Kallman syndrome, luteinizing hormone-releasing hormone deficiency, and dysfunction of the pituitary-hypothalamic axis. Despite their therapeutic benefits, anabolic steroids are frequently misused due to their ability to enhance muscle size and strength, which can lead to significant adverse effects and long-term health risks.

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Conflict of interest statement

Disclosure: Stephen Leslie declares no relevant financial relationships with ineligible companies.

Disclosure: Sajedur Rahman declares no relevant financial relationships with ineligible companies.

Disclosure: Kavitha Ganesan declares no relevant financial relationships with ineligible companies.

References

    1. Yesalis CE, Kennedy NJ, Kopstein AN, Bahrke MS. Anabolic-androgenic steroid use in the United States. JAMA. 1993 Sep 08;270(10):1217-21. - PubMed
    1. Hildebrandt T, Harty S, Langenbucher JW. Fitness supplements as a gateway substance for anabolic-androgenic steroid use. Psychol Addict Behav. 2012 Dec;26(4):955-62. - PMC - PubMed
    1. Piacentino D, Kotzalidis GD, Del Casale A, Aromatario MR, Pomara C, Girardi P, Sani G. Anabolic-androgenic steroid use and psychopathology in athletes. A systematic review. Curr Neuropharmacol. 2015 Jan;13(1):101-21. - PMC - PubMed
    1. Lusetti M, Licata M, Silingardi E, Bonsignore A, Palmiere C. Appearance/Image- and Performance-Enhancing Drug Users: A Forensic Approach. Am J Forensic Med Pathol. 2018 Dec;39(4):325-329. - PubMed
    1. Jones IA, Togashi R, Hatch GFR, Weber AE, Vangsness CT. Anabolic steroids and tendons: A review of their mechanical, structural, and biologic effects. J Orthop Res. 2018 Nov;36(11):2830-2841. - PubMed

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