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Book

Phenytoin Toxicity

Alexandru Iorga  1 , B. Zane Horowitz  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Affiliations
Book

Phenytoin Toxicity

Alexandru Iorga et al.

Excerpt

Since its discovery in 1908, phenytoin has become one of the most well-studied anticonvulsants. With an average monthly cost of $30, it has also become one of the most widely used anticonvulsants, listed on the World Health Organization’s List of Essential Medicines. However, with its narrow therapeutic index and its pervasive daily use, considering potential phenytoin overdose or toxicity from chronic use is key to early management and prevention of further toxicity.

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Conflict of interest statement

Disclosure: Alexandru Iorga declares no relevant financial relationships with ineligible companies.

Disclosure: B. Zane Horowitz declares no relevant financial relationships with ineligible companies.

References

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