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. 2015;1(1):7.
doi: 10.1186/s40981-015-0009-2. Epub 2015 Aug 27.

Comparison between succinylcholine and rocuronium as neuromuscular blocking agents for electroconvulsive therapy in a patient with pseudocholinesterase deficiency

Tomonori Takazawa  1 , Takashi Suto  1 , Masako Aihara  2 , Takeshi Anzai  1 , Tatsuo Horiuchi  1 , Makiko H Yamada  1 , Yuji Kadoi  1 , Shigeru Saito  1
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Comparison between succinylcholine and rocuronium as neuromuscular blocking agents for electroconvulsive therapy in a patient with pseudocholinesterase deficiency

Tomonori Takazawa et al. JA Clin Rep. 2015.

Abstract

We report here the anesthetic management of a patient with schizophrenia and pseudocholinesterase deficiency. Electroconvulsive therapy was performed using succinylcholine and rocuronium as the neuromuscular blocking agents in the first seven and latter six treatments, respectively. The recovery time from muscle relaxation after succinylcholine administration was remarkably longer than that after rocuronium-sugammadex administration. Rocuronium and sugammadex appear to be useful in situations in which succinylcholine is contraindicated.

Keywords: Anesthesia; Electroconvulsive therapy; Rocuronium; Sugammadex.

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Figures

Fig. 1
Fig. 1
The comparison of EEG seizure duration (a) and time to shifting from operation room (b) between treatment with SCC and ROC-sugammadex. Data are mean ± SD. *P < 0.05, Mann-Whitney Rank Sum Test
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