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Case Reports
. 2018 Jun;97(6):1081-1083.
doi: 10.1007/s00277-018-3257-1. Epub 2018 Mar 1.

Progressive transformation of germinal centers: an illustration of two clinical cases

Konrad Tałasiewicz  1 , Aleksandra Czachowska  2 , Katarzyna Śmiałek-Kania  2 , Dominika Jaxa-Larecka  2 , Beata Jagielska  2
Affiliations
Case Reports

Progressive transformation of germinal centers: an illustration of two clinical cases

Konrad Tałasiewicz et al. Ann Hematol. 2018 Jun.
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
a Ultrasound photograph of the hypoechoic lymph node, case 1. b PET-CT with FDG demonstrating increased uptake of the radiotracer at different levels on the both sides of the neck, case 1. c MRI showing enlarged submandibular lymph node with contrast enhancement, case 2. d Histopathology micrographs, D1. H&E staining with follicles of varying sizes and shapes with eccentric mantle layers surrounding their germinal centers, D2. BCL6 staining—normal distribution (BCL6 is noted in a high proportion of Hodgkin’s disease cells), D3. BCL2 staining—normal distribution (mantle zone and T cells are positive but germinal center is negative). It helps distinguishing from follicular lymphoma (germinal centers are BCL2+), case 2
See this image and copyright information in PMC

References

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