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Review
. 2018 Jun;20(3):235-247.
doi: 10.1007/s40272-018-0287-z.

The Management of Paediatric Functional Abdominal Pain Disorders: Latest Evidence

Affiliations
Review

The Management of Paediatric Functional Abdominal Pain Disorders: Latest Evidence

Andrea Brusaferro et al. Paediatr Drugs. 2018 Jun.

Abstract

Recurrent abdominal pain (RAP) is one of the most common health complaints in both children and adults. Although RAP is considered a functional disorder rather than an organic disease, affected children and their families can still experience anxiety and concerns that can interfere with school, sports, and regular daily activities and lead to frequent attendances at pediatric emergency departments or pediatric gastroenterology clinics. Our review shows experts do not agree on a universally proven management that will work on every child presenting with functional abdominal pain (FAP). Treatment strategies include both non-pharmacological and pharmacological options. Non-pharmacological treatments are usually very well accepted by both children and their parents and are free from medication side effects. Nevertheless, they may be as effective as the pharmacological interventions; therefore, according to many experts and based on the majority of current evidence, a non-pharmacological approach should be the first intervention attempt in children with RAP. In particular, the importance of the bio-psychosocial approach is highlighted, as a majority of children will improve with counselling and reassurance that no serious organic pathologies are suspected, especially when the physician establishes a trustful relationship with both the child and their family. Placebo and pharmacological interventions could be attempted when the bio-psychosocial approach is not applicable or not efficacious. In some difficult cases, finding an effective treatment for FAP can be a challenge, and a number of strategies may need to be tried before symptoms are controlled. In these cases, a multidisciplinary team, comprising a pediatric gastroenterologist, dietician, psychologist, and psychotherapist, is likely to be successful.

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Conflict of interest statement

Funding

No sources of funding were used to conduct this study or prepare this manuscript.

Conflict of interest

Andrea Brusaferro, Edoardo Farinelli, Letizia Zenzeri, Rita Cozzali, Susanna Esposito have no conflicts of interest that are directly relevant to the content of this manuscript.

References

    1. Gomez-Suarez R. Difficulties in the diagnosis and management of functional or recurrent abdominal pain in children. Pediatr Ann. 2016;45:e388–e393. doi: 10.3928/19382359-20161019-01. - DOI - PubMed
    1. Tringali A, Thomson M, Dumonceau JM, Tavares M, Tabbers MM, Furlano R, Spaander M, Hassan C, Tzvinikos C, Ijsselstijn H, Viala J, Dall’Oglio L, Benninga M, Orel R, Vandenplas Y, Keil R, Romano C, Brownstone E, Hlava Š, Gerner P, Dolak W, Landi R, Huber WD, Everett S, Vecsei A, Aabakken L, Amil-Dias J, Zambelli A. Pediatric gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) and European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) Guideline Executive summary. Endoscopy. 2017;49:83–91. - PubMed
    1. Clouse RE, Mayer EA, Aziz Q, Drossman DA, Dumitrascu DL, Mönnikes H, Naliboff BD. Functional abdominal pain syndrome. Gastroenterology. 2006;130:1492–1497. doi: 10.1053/j.gastro.2005.11.062. - DOI - PubMed
    1. Paul SP, Basude D. Non-pharmacological management of abdominal painrelated functional gastrointestinal disorders in children. Torquay, UK World J Pediatr, 2016. Available at: http://www.wjpch.com. Accessed 30 Oct 2017. - PubMed
    1. Sharpstone D, Colin-Jones DG. Chronic, non-visceral abdominal pain. Gut. 1994;35:833–836. doi: 10.1136/gut.35.6.833. - DOI - PMC - PubMed