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. 2018 Mar 1;22(3):281-282.
doi: 10.1016/j.stem.2018.02.008.

Living Up to the Hype: Protein Synthesis Promotes Hypertranscription in Embryonic Stem Cells

Miriama Kruta  1 , Robert A J Signer  2
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Living Up to the Hype: Protein Synthesis Promotes Hypertranscription in Embryonic Stem Cells

Miriama Kruta et al. Cell Stem Cell. .
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Abstract

The rapid proliferation and unlimited self-renewal of embryonic stem cells depends upon a permissive chromatin landscape that enables hypertranscription. In this issue of Cell Stem Cell, Bulut-Karslioglu et al. report that euchromatin and transcriptional output are enhanced by protein synthesis in embryonic stem cells (Bulut-Karslioglu et al., 2018).

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