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Review
. 2018 Mar;41(3):122-124.
doi: 10.1016/j.tins.2018.01.001.

Cell Type-Specific Optogenetic Dissection of Brain Rhythms

Affiliations
Review

Cell Type-Specific Optogenetic Dissection of Brain Rhythms

Hillel Adesnik. Trends Neurosci. 2018 Mar.

Abstract

A pair of 2009 papers by Cardin et al. and Sohal et al. marked a watershed moment as optogenetics exploded onto the scene of systems neuroscience. This pair of back-to-back papers in the June issue of Nature leveraged a powerful combination of the Cre/lox system, adeno-associated viral gene vectors, and optogenetics to re-examine the circuit basis of neuronal synchronization.

Keywords: gamma rhythms; optogenetics; parvalbumin interneurons.

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