The kidney gets caught in a macrophage trap
- PMID: 29500227
- DOI: 10.1126/sciimmunol.aat3745
The kidney gets caught in a macrophage trap
Abstract
Myoglobulin released from dead muscle is shown to induce acute kidney injury through a mechanism dependent on platelets and macrophage extracellular traps.
Copyright © 2018, American Association for the Advancement of Science.
Comment on
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Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury.Nat Med. 2018 Feb;24(2):232-238. doi: 10.1038/nm.4462. Epub 2018 Jan 8. Nat Med. 2018. PMID: 29309057
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