Candida auris for the clinical microbiology laboratory: Not your grandfather's Candida species
- PMID: 29503491
- PMCID: PMC5831145
- DOI: 10.1016/j.clinmicnews.2017.06.003
Candida auris for the clinical microbiology laboratory: Not your grandfather's Candida species
Abstract
Candida auris is a newly emerging species that was first identified in Asia in 2009 but has rapidly spread across the world. C. auris differs from most other Candida species in that antifungal resistance is the norm rather than the exception, it is a commensal of human skin rather than the human gut, and it can be easily transmitted from person to person in a healthcare setting. This review discusses the emergence of C. auris, global epidemiology, identification, antifungal susceptibility testing, and precautions to be taken when it is identified from a patient specimen.
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References
-
- Satoh K, Makimura K, Hasumi Y, Nishiyama Y, Uchida K, Yamaguchi H. Candida auris sp.nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital. Microbiology and immunology. 2009;53(1):41–4. - PubMed
-
- Chowdhary A, Anil Kumar V, Sharma C, et al. Multidrug-resistant endemic clonal strain of Candida auris in India. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2014;33(6):919–26. - PubMed
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