Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Mar;84(5):1374-8.
doi: 10.1073/pnas.84.5.1374.

Identification of a monoclonal antibody specific for a murine T3 polypeptide

O Leo, M Foo, D H Sachs, L E Samelson, J A Bluestone

Identification of a monoclonal antibody specific for a murine T3 polypeptide

O Leo et al. Proc Natl Acad Sci U S A. 1987 Mar.

Abstract

A monoclonal antibody (145-2C11) specific for the murine T3 complex was derived by immunizing Armenian hamsters with a murine cytolytic T-cell clone. The antibody is specific for a 25-kDa protein component (T3-epsilon) of the antigen-specific T-cell receptor. It reacts with all mature T cells and can both activate and inhibit T-cell function. These results identify T3-epsilon as a cell surface protein involved in the transduction of activation signals.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1985 Apr;82(7):1969-73 - PubMed
    1. J Immunol. 1986 Dec 15;137(12):3874-80 - PubMed
    1. J Immunol. 1985 Jul;135(1):5-8 - PubMed
    1. Nature. 1985 Oct 17-23;317(6038):627-9 - PubMed
    1. Nature. 1986 Jul 10-16;322(6075):145-9 - PubMed