Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
- PMID: 29505510
- PMCID: PMC5943132
- DOI: 10.1097/MD.0000000000009243
Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer
Abstract
This study aimed to explore the efficacy and toxicity of image-guided stereotactic body radiotherapy (IGSBR) by helical tomotherapy in patients with lung cancer among Chinese Han population.A total of 21 patients with stage I lung cancer were included. They received a total of 60 Gy factions IGSBR. The outcomes included complete response (CR), partial response (PR), stable disease (SD), progress disease (PD), overall response rate (ORR), and overall survival (OS). In addition, toxicities were also recorded in this study.Three-year CR, PR, SD, PD, ORR, and OS were 47.6%, 38.1%, 9.5%, 4.8%, 85.7%, and 48.0 months, respectively. Additionally, mild toxicities were found in this study.This study demonstrated that IGSBR is efficacious for patients with stage I lung cancer with mild toxicities among Chinese Han population.
Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.
Conflict of interest statement
The authors have no conflicts of interest to disclose.
Similar articles
-
Comparison of Effects Between Central and Peripheral Stage I Lung Cancer Using Image-Guided Stereotactic Body Radiotherapy via Helical Tomotherapy.Technol Cancer Res Treat. 2015 Dec;14(6):701-7. doi: 10.1177/1533034615583206. Epub 2015 Apr 24. Technol Cancer Res Treat. 2015. PMID: 25911646
-
Feasibility report of image guided stereotactic body radiotherapy (IG-SBRT) with tomotherapy for early stage medically inoperable lung cancer using extreme hypofractionation.Acta Oncol. 2006;45(7):890-6. doi: 10.1080/02841860600907329. Acta Oncol. 2006. PMID: 16982555 Clinical Trial.
-
Helical image-guided stereotactic body radiotherapy (SBRT) for the treatment of early-stage lung cancer: a single-institution experience at the Willis-Knighton Cancer Center.Tumori. 2014 Jan-Feb;100(1):42-8. doi: 10.1700/1430.15814. Tumori. 2014. PMID: 24675490
-
A Large, Multicenter, Retrospective Study on Efficacy and Safety of Stereotactic Body Radiotherapy (SBRT) in Oligometastatic Ovarian Cancer (MITO RT1 Study): A Collaboration of MITO, AIRO GYN, and MaNGO Groups.Oncologist. 2020 Feb;25(2):e311-e320. doi: 10.1634/theoncologist.2019-0309. Epub 2019 Oct 10. Oncologist. 2020. PMID: 32043791 Free PMC article.
-
Toxicity and outcome results of a class solution with moderately hypofractionated radiotherapy in inoperable Stage III non-small cell lung cancer using helical tomotherapy.Int J Radiat Oncol Biol Phys. 2010 Aug 1;77(5):1352-9. doi: 10.1016/j.ijrobp.2009.06.075. Epub 2010 Jan 7. Int J Radiat Oncol Biol Phys. 2010. PMID: 20056350
Cited by
-
Postoperative radiotherapy in pIIIA-N2 non-small cell lung cancer after complete resection and adjuvant chemotherapy: A meta-analysis.Medicine (Baltimore). 2022 Jul 15;101(28):e29550. doi: 10.1097/MD.0000000000029550. Medicine (Baltimore). 2022. PMID: 35839025 Free PMC article.
-
Clinical impact of postoperative radiotherapy in pIII-N2 non-small cell lung cancer after complete resection followed by adjuvant chemotherapy: a systematic review and meta-analysis.J Thorac Dis. 2024 Mar 29;16(3):1815-1824. doi: 10.21037/jtd-23-1742. Epub 2024 Mar 15. J Thorac Dis. 2024. PMID: 38617755 Free PMC article.
References
-
- Rami-Porta R, Crowley JJ, Goldstraw P. The revised TNM staging system for lung cancer. Ann Thorac Cardiovasc Surg 2009;15:4–9. - PubMed
-
- Falkson CB, Vella ET, Yu E, et al. Radiotherapy with curative intent in patients with early-stage, medically inoperable, non-small-cell lung cancer: a systematic review. Clin Lung Cancer 2017;18:105–21. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials