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. 2018 Mar 5;13(3):e0193728.
doi: 10.1371/journal.pone.0193728. eCollection 2018.

Physical activity and sedentary behavior in patients with Systemic Lupus Erythematosus

Domenico Paolo Emanuele Margiotta  1 , Fabio Basta  1 , Giulio Dolcini  1 , Veronica Batani  1 , Marina Lo Vullo  1 , Alessia Vernuccio  1 , Luca Navarini  1 , Antonella Afeltra  1
Affiliations

Physical activity and sedentary behavior in patients with Systemic Lupus Erythematosus

Domenico Paolo Emanuele Margiotta et al. PLoS One. .

Abstract

Introduction: The aim of this study was to evaluate the proportion of patients with Systemic Lupus Erythematosus (SLE) who did not met the WHO recommendations for physical activity and to evaluate the amount of time spent in sedentary behavior.

Methods: SLE patients were consecutively enrolled in a cross sectional study. The type and the time spent in physical activity and sedentary behavior were evaluated using the IPAQ short form questionnaire. The adequate physical activity was defined according to the 2010 WHO recommendations for health and the sedentary behavior according to the 2017 SBRN consensus. We also assessed quality of life using SF-36, mood disorders using BDI and HAM-H, fatigue using Facit-Fatigue and sleep disorders using PSQI scores.

Results: Physical activity was not sufficient to meet WHO recommendations in 56 of 93 SLE patients (60%). SLE patients spent a median (95% range) of 180 (0-600) minutes everyday in sedentary activities. The length of daily sedentary time was more than 6 hours in 25% of SLE patients. In multivariable analysis, the factors associated to the probability of not meeting WHO criteria was only the time of exposure to antimalarials (OR 0.88, p 0.03) and the factors related to the probability of being in the upper tertile of sedentary time (more than 270 minutes) were age (OR 1.04, p 0.02), disease activity expressed by SELENA-SLEDAI score (OR 1.2, p 0.01) and Facit-fatigue score (OR 0.94, p 0.04).

Conclusion: A relevant proportion of SLE patients were inadequately physically active. It is essential to improve the awareness of the importance of increase physical activity and reduce sedentary time. A better control of disease activity and fatigue and a prolonged use of antimalarials could help to reach this notable goal.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

References

    1. Reddigan JI, Ardern CI, Riddell MC, Kuk JL. Relation of physical activity to cardiovascular disease mortality and the influence of cardiometabolic risk factors. Am J Cardiol. 2011;108(10):1426–31. doi: 10.1016/j.amjcard.2011.07.005 . - DOI - PubMed
    1. WHO. Global recommendations on physical activity for health: WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland; 2010.
    1. Pate RR, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C, et al. Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA. 1995;273(5):402–7. . - PubMed
    1. Bell JA, Hamer M, Batty GD, Singh-Manoux A, Sabia S, Kivimaki M. Combined effect of physical activity and leisure time sitting on long-term risk of incident obesity and metabolic risk factor clustering. Diabetologia. 2014;57(10):2048–56. doi: 10.1007/s00125-014-3323-8 . - DOI - PMC - PubMed
    1. Sharif K, Watad A, Bragazzi NL, Lichtbroun M, Amital H, Shoenfeld Y. Physical activity and autoimmune diseases: Get moving and manage the disease. Autoimmun Rev. 2017. doi: 10.1016/j.autrev.2017.11.010 . - DOI - PubMed