Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis
- PMID: 29508607
- DOI: 10.1021/acs.orglett.8b00408
Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis
Erratum in
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Correction to "Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis".Org Lett. 2018 Apr 20;20(8):2504. doi: 10.1021/acs.orglett.8b00948. Epub 2018 Apr 2. Org Lett. 2018. PMID: 29608065 No abstract available.
Abstract
A nickel-catalyzed reductive cascade approach to the efficient construction of diastereodivergent cores embedded in podophyllum lignans is developed for the first time. Their gram-scale access paved the way for unified syntheses of naturally occurring podophyllotoxin and other members.
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