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Case Reports
. 1987 Feb;116(2):241-2.
doi: 10.1111/j.1365-2133.1987.tb05819.x.

Trimethoprim associated fixed drug eruption

B R Hughes, P J Holt, R Marks
Case Reports

Trimethoprim associated fixed drug eruption

B R Hughes et al. Br J Dermatol. 1987 Feb.

Abstract

We report two cases of fixed drug eruption due to trimethoprim. Fixed drug eruption is a distinct entity characterized by the development of circular erythematous skin lesions which over a period of time become violaceous and leave an area of hyperpigmentation. Mucous membranes also may be affected. With re-administration of the drug the lesions recur in the same area but may extend to further new areas with each challenge.

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