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. 2018 Mar 5;8(1):7.
doi: 10.3390/life8010007.

Potential Role of Inorganic Confined Environments in Prebiotic Phosphorylation

Avinash Vicholous Dass  1 , Maguy Jaber  2 , André Brack  3 , Frédéric Foucher  4 , Terence P Kee  5 , Thomas Georgelin  6   7 , Frances Westall  8
Affiliations

Potential Role of Inorganic Confined Environments in Prebiotic Phosphorylation

Avinash Vicholous Dass et al. Life (Basel). .

Abstract

A concise outlook on the potential role of confinement in phosphorylation and phosphate condensation pertaining to prebiotic chemistry is presented. Inorganic confinement is a relatively uncharted domain in studies concerning prebiotic chemistry, and even more so in terms of experimentation. However, molecular crowding within confined dimensions is central to the functioning of contemporary biology. There are numerous advantages to confined environments and an attempt to highlight this fact, within this article, has been undertaken, keeping in context the limitations of aqueous phase chemistry in phosphorylation and, to a certain extent, traditional approaches in prebiotic chemistry.

Keywords: hydrogels; interface; nanoscopic confinement; phosphorylation; prebiotic chemistry.

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Conflict of interest statement

The author declares no conflicts of interest.

Figures

Figure 1
Figure 1
Water types in confined system.
Figure 2
Figure 2
Cryosem image of silica hydrogel prepared by a sol/gel methods from a mixture of sodium silicate and acetic acid solutions. Pore size around 2 µm.
See this image and copyright information in PMC

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