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. 2018 Mar 6;18(1):109.
doi: 10.1186/s12879-018-2998-8.

High seroprevalence of syphilis infection among pregnant women in Yiregalem hospital southern Ethiopia

Anteneh Amsalu  1 , Getachew Ferede  2 , Demissie Assegu  3
Affiliations

High seroprevalence of syphilis infection among pregnant women in Yiregalem hospital southern Ethiopia

Anteneh Amsalu et al. BMC Infect Dis. .

Abstract

Background: Despite availability of effective treatment and the implementation of focused antenatal care (ANC), still the prevalence of syphilis persists in Ethiopia. Yet, data is not found in southern Ethiopia. Therefore, this study was conducted to determine the seroprevalence and associated factors of syphilis among pregnant women in Yiregalem Hospital, Southern Ethiopia.

Methods: A cross-sectional study was conducted among pregnant women from October 2015 to August 2016. Data on socio-demography and obstetric conditions of pregnant women were collected using a structured questionnaire. Serum samples were screened for syphilis using rapid plasma regain (RPR) test and those found seropositive were further confirmed by Treponema pallidum haemagglutination assay (TPHA) test following the manufacturer's instruction. HIV results were reviewed from records. The data were analyzed using SPSS version 20 software.

Results: Of 494 pregnant women, 204(41.3%) were first ANC visit attenders. Of these, 123(60.3%) were after the 12th gestational week. Sero-prevalence of syphilis and HIV was found to be 5.1% (25/494; 95 CI, 3.2-7.1%) and 10.3% (51/494; 95 CI, 7.7-13.2%), respectively. The overall prevalence of syphilis and HIV co-infection was 2.2% (11/494). Women with HIV infection were significantly more likely to be syphilis-seropositive (AOR = 10.3, 95%CI, 4.213-25.185) than HIV negatives.

Conclusions: High seroprevalence of syphilis particularly among HIV positive women and late first ANC visit attenders in the study area calls for further ramping up of current intervention measures. Like integration of syphilis testing and treatment to the already established HIV prevention program and creating awareness about early ANC visit and follow-up.

Keywords: Ethiopia; Pregnant women; Syphilis.

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Conflict of interest statement

Ethics approval and consent to participate

The study was approved by the Institutional Review Board of the College of Medicine and Health Sciences, Hawassa University and informed written consent was obtained from the study participants.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no computing interests.

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Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

References

    1. World Health Organization . Baseline report on global sexually transmitted infection surveillance 2013. Geneva (Switzerland): World Health Organization; 2014.
    1. Karp G, Schlaeffer F, Jotkowitz A, Riesenberg K. Syphilis and HIV co-infection. Eur J intern med. 2009;20(1):9–13. doi: 10.1016/j.ejim.2008.04.002. - DOI - PubMed
    1. The Ethiopian Public Health Institute . Report on the 2014 round antenatal care based sentinel HIV surveillance in Ethiopia. 2015.
    1. Assefa A. A three year retrospective study on Seroprevalence of syphilis among pregnant women at Gondar University teaching hospital, Ethiopia. Afr Health Sci. 2014;14(1):119–24. 10.4314/ahs.v14i1.18 - PMC - PubMed
    1. Melku M, Kebede A, Addis Z. Magnitude of HIV and syphilis seroprevalence among pregnant women in gondar, northwest ethiopia: a cross-sectional study. HIV/AIDS. 2015;7:175. - PMC - PubMed

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