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Comment
. 2018 Mar 6;27(3):481-482.
doi: 10.1016/j.cmet.2018.02.012.

Food for Training-Western Diet and Inflammatory Memory

Parimal Samir  1 , R K Subbarao Malireddi  1 , Thirumala-Devi Kanneganti  2
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Free article
Comment

Food for Training-Western Diet and Inflammatory Memory

Parimal Samir et al. Cell Metab. .
Free article

Abstract

In recent years, trained immunity has emerged as an attractive concept to explain cross-protection against pathogens mediated by the innate immune system. Using a diet-based sterile inflammation model, Christ et al. (2018) have shown in a recent issue of Cell that trained immunity may also play a critical role in responding to diet and endogenous sterile triggers.

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  • Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
    Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E. Christ A, et al. Cell. 2018 Jan 11;172(1-2):162-175.e14. doi: 10.1016/j.cell.2017.12.013. Cell. 2018. PMID: 29328911 Free PMC article.

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