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. 2018 Jul 15;34(14):2483-2484.
doi: 10.1093/bioinformatics/bty127.

PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

Giovanna Ambrosini  1   2 , Romain Groux  1   2 , Philipp Bucher  1   2
Affiliations

PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

Giovanna Ambrosini et al. Bioinformatics. .

Abstract

Summary: Transcription factors regulate gene expression by binding to specific short DNA sequences of 5-20 bp to regulate the rate of transcription of genetic information from DNA to messenger RNA. We present PWMScan, a fast web-based tool to scan server-resident genomes for matches to a user-supplied PWM or transcription factor binding site model from a public database.

Availability and implementation: The web server and source code are available at http://ccg.vital-it.ch/pwmscan and https://sourceforge.net/projects/pwmscan, respectively.

Supplementary information: Supplementary data are available at Bioinformatics online.

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Figures

Fig. 1.
Fig. 1.
Screen shot of the PWMScan graphical user interface
See this image and copyright information in PMC

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