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Case Reports
. 2017 Oct 10:28:132.
doi: 10.11604/pamj.2017.28.132.5607. eCollection 2017.

[Ankylosing spondylitis associated with Still's disease: should it be considered a pathophysiologic link or a simple association?]

[Article in French]
Nassira Aradoini  1 , Sofia Talbi  1 , Hamida Azzouzi  1 , Fatima Zahra Abourazzak  1 , Hajar Khibri  2 , Rhizlane Berrady  2 , Wafaa Bono  2 , Taoufik Harzy  1
Affiliations
Case Reports

[Ankylosing spondylitis associated with Still's disease: should it be considered a pathophysiologic link or a simple association?]

[Article in French]
Nassira Aradoini et al. Pan Afr Med J. .

Abstract
in English, French

Ankylosing spondylitis is a chronic inflammatory rheumatism; it is part of the group of spondyloarthrites. General signs such as fever and weight loss are of little importance. Adult Still's disease is a rare systemic condition, a diagnosis of exclusion commonly characterized by high hectic fever, rash, arthritis and various systemic manifestations. Few cases of ankylosing spondylitis associated with adult Still's disease have been described in the literature. We here report the case of a 31-year old patient followed up for ankylosing spondylitis presenting with fever which had lasted for a long time and clinico-biological signs compatible with adult Still's disease. A possible pathophysiologic link between the two diseases may be suggested, even if their simultaneous occurrence has been rarely reported in the literature.

La spondylarthrite ankylosante est un rhumatisme inflammatoire chronique,qui fait partie des groupes de spondyloarthrites, au cours duquel les signes généraux comme la fièvre et l'amaigrissement sont peu importants. La maladie de Still de l'adulte est une affection systémique rare, qui reste un diagnostic d'élimination, et qui associe classiquement une fièvre élevée hectique, une éruption cutanée, des arthrites, et des manifestations systémiques diverses. Peu de cas de spondylarthrites ankylosantes présentés avec un tableau de la maladie de Still de l'adulte ont été décrits dans la littérature. Nous rapportons un nouveau cas d'un patient de 31ans suivi pour spondylarthrite ankylosante et qui se présente avec une fièvre au long cours et des signes clinico-biologiques entrant dans le cadre de la maladie de Still de l'adulte. Un éventuel lien physiopathologique entre les deux pathologies peut être évoqué, même si leur survenue simultanée est rarement rapportée dans la littérature.

Keywords: Ankylosing spondylitis; Still; fever; glucocorticoids.

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Figures

Figure 1
Figure 1
TDM du bassin, coupe frontale, objectivant une sacroiliite avec condensation des berges et érosions
Figure 2
Figure 2
Rash cutané rose saumon maculo-papuleux et prurigineux
See this image and copyright information in PMC

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References

    1. Arlet JB, Gentelle S, Grasland A, Pouchot J, Vinceneux P. Les formes fébriles de laspondylarthrite ankylosante. Rev Med Interne. 2002 Jan;23(1):81–4. - PubMed
    1. Rudwaleit M, van der Heijde D, Landewé R, Akkoc N, Brandt J, Chou CT, et al. The Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritisand for spondyloarthritis in general. Ann Rheum Dis. 2011 Jan;70(1):25–31. - PubMed
    1. Akkoc N, Sari I, Birlik M, Pay S, Binicier O, Akar S, Onen F. Ankylosing spondylitis and spondylarthropathy presenting with a clinical picture of adult onset Still's disease: case series. Rheumatology (Oxford). 2008 Sep;47(9):1436–7. - PubMed
    1. Carter ME. Sacro-iliitis in Still's disease. Ann Rheum Dis. 1962 Jun;21(2):105–20. - PMC - PubMed
    1. Cush JJ. The University of Texas Southwestern Medical Center at Dallas. 1994. Jan 5, Adult-onset still's disease-a circadian syndrome? Internal Medicine Grand Rounds. Accessed on 05 January 2015.

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