Vascular Mineralization in Pseudoxanthoma Elasticum: Etidronate to the Rescue?

Affiliations

¹ Department of Dermatology and Cutaneous Biology, Jefferson Institute of Molecular Medicine, Sidney Kimmel Medical College, and PXE International Center of Excellence in Research and Clinical Care, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: Jouni.Uitto@jefferson.edu.
² Department of Dermatology and Cutaneous Biology, Jefferson Institute of Molecular Medicine, Sidney Kimmel Medical College, and PXE International Center of Excellence in Research and Clinical Care, Thomas Jefferson University, Philadelphia, Pennsylvania.

Free article

Editorial

Jouni Uitto et al. J Am Coll Cardiol. 2018.

Free article

. 2018 Mar 13;71(10):1127-1129.

doi: 10.1016/j.jacc.2018.01.018.

¹ Department of Dermatology and Cutaneous Biology, Jefferson Institute of Molecular Medicine, Sidney Kimmel Medical College, and PXE International Center of Excellence in Research and Clinical Care, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: Jouni.Uitto@jefferson.edu.
² Department of Dermatology and Cutaneous Biology, Jefferson Institute of Molecular Medicine, Sidney Kimmel Medical College, and PXE International Center of Excellence in Research and Clinical Care, Thomas Jefferson University, Philadelphia, Pennsylvania.

No abstract available

Keywords: bisphosphonates; etidronate; inorganic pyrophosphate; pseudoxanthoma elasticum; vascular mineralization.

Comment on

Etidronate for Prevention of Ectopic Mineralization in Patients With Pseudoxanthoma Elasticum.
Kranenburg G, de Jong PA, Bartstra JW, Lagerweij SJ, Lam MG, Ossewaarde-van Norel J, Risseeuw S, van Leeuwen R, Imhof SM, Verhaar HJ, de Vries JJ, Slart RHJA, Luurtsema G, den Harder AM, Visseren FLJ, Mali WP, Spiering W. Kranenburg G, et al. J Am Coll Cardiol. 2018 Mar 13;71(10):1117-1126. doi: 10.1016/j.jacc.2017.12.062. J Am Coll Cardiol. 2018. PMID: 29519353 Clinical Trial.