Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1987 Feb;31(2):343-5.
doi: 10.1128/AAC.31.2.343.

In vitro activity of a new macrolide, A-56268, compared with that of roxithromycin, erythromycin, and clindamycin

A L Barry, C Thornsberry, R N Jones
Comparative Study

In vitro activity of a new macrolide, A-56268, compared with that of roxithromycin, erythromycin, and clindamycin

A L Barry et al. Antimicrob Agents Chemother. 1987 Feb.

Abstract

A new macrolide (A-56268) was found to be approximately twice as active as erythromycin and four to eight times more active than roxithromycin. All three macrolides were similar in their potency against anaerobes. Human plasma enhanced the antistaphylococcal activity of A-56268 and erythromycin but reduced the activities of roxithromycin and clindamycin.

PubMed Disclaimer

References

    1. Antimicrob Agents Chemother. 1972 May;1(5):433-40 - PubMed
    1. Antimicrob Agents Chemother. 1979 Feb;15(2):243-5 - PubMed
    1. Antimicrob Agents Chemother. 1981 Feb;19(2):335-6 - PubMed
    1. Antimicrob Agents Chemother. 1983 Aug;24(2):209-15 - PubMed
    1. Antimicrob Agents Chemother. 1976 Oct;10(4):727-32 - PubMed

Publication types

MeSH terms