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Review
. 2018 Apr;9(2):545-550.
doi: 10.1007/s13300-018-0394-4. Epub 2018 Mar 8.

Herpes Zoster and Diabetes Mellitus: A Review

Marianthi Papagianni  1 , Symeon Metallidis  1 , Konstantinos Tziomalos  2
Affiliations
Review

Herpes Zoster and Diabetes Mellitus: A Review

Marianthi Papagianni et al. Diabetes Ther. 2018 Apr.

Abstract

Accumulating evidence suggests that diabetes mellitus (DM) represents an important risk factor for both herpes zoster and post-herpetic neuralgia. Moreover, post-herpetic neuralgia appears to be more severe and persistent in diabetic patients. On the other hand, a novel vaccine against varicella-zoster virus (VZV) was recently introduced in clinical practice. Given the increased risk and severity of herpes zoster infection in patients with DM, this vaccine might be useful in this population. However, there are limited data regarding the efficacy and safety of vaccination against herpes zoster in the diabetic population. The aim of the present review is to discuss the incidence and consequences of herpes zoster infection in DM and to comment on the role of vaccination against VZV in these patients.

Keywords: Adjuvanted vaccine; Diabetes mellitus; Herpes zoster; Live attenuated vaccine; Post-herpetic neuralgia; Vaccination.

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