Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jun 1;187(6):1149-1152.
doi: 10.1093/aje/kwy036.

Diesel Exhaust and Lung Cancer-Aftermath of Becoming an IARC Group 1 Carcinogen

Debra T Silverman  1
Affiliations

Diesel Exhaust and Lung Cancer-Aftermath of Becoming an IARC Group 1 Carcinogen

Debra T Silverman. Am J Epidemiol. .

Abstract

The International Agency for Research on Cancer reclassified diesel exhaust from Group 2A (probably carcinogenic to humans) to Group 1 (carcinogenic to humans) in 2012. Since then, reevaluation and reanalysis of 2 major studies (Diesel Exhaust in Miners Study and Trucking Industry Particle Study) that were influential to the International Agency for Research on Cancer evaluation have replicated the original findings and demonstrated the suitability of these epidemiologic data for the quantitative risk assessment needed to set safe exposure limits in occupational and outdoor ambient environments. The challenge now is to protect the workers and general populations in urban areas from the carcinogenicity of diesel exhaust.

PubMed Disclaimer

Comment in

References

    1. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Diesel and gasoline engine exhausts and some nitroarenes. IARC Monogr Eval Carcinog Risks Hum. 2014;105:9–699. - PMC - PubMed
    1. Silverman DT. Is diesel exhaust a human lung carcinogen? [editorial]. Epidemiology. 1998;9(1):4–6. - PubMed
    1. Silverman DT, Samanic CM, Lubin JH, et al. . The Diesel Exhaust in Miners Study: a nested case-control study of lung cancer and diesel exhaust. J Natl Cancer Inst. 2012;104(11):855–868. - PMC - PubMed
    1. Attfield MD, Schleiff PL, Lubin JH, et al. . The Diesel Exhaust in Miners Study: a cohort mortality study with emphasis on lung cancer. J Natl Cancer Inst. 2012;104(11):869–883. - PMC - PubMed
    1. Garshick E, Laden F, Hart JE, et al. . Lung cancer and elemental carbon exposure in trucking industry workers. Environ Health Perspect. 2012;120(9):1301–1306. - PMC - PubMed

Publication types

Substances