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. 2018 Apr 6;20(7):1794-1797.
doi: 10.1021/acs.orglett.8b00292. Epub 2018 Mar 9.

Direct Dehydrogenative Arylation of Benzaldehydes with Arenes Using Transient Directing Groups

Da-Yu Wang  1 , Shi-Huan Guo  1 , Gao-Fei Pan  1 , Xue-Qing Zhu  1 , Ya-Ru Gao  1 , Yong-Qiang Wang  1
Affiliations

Direct Dehydrogenative Arylation of Benzaldehydes with Arenes Using Transient Directing Groups

Da-Yu Wang et al. Org Lett. .

Abstract

The utilization of the transient directing strategy into the direct oxidative dehydrogenative arylation of aldehydes with arenes was reported for the first time. Featured by mild reaction conditions, good functional group compatibility, and great regioselectivity, the method should find broad applications in new medicine and material development and discovery processes.

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