The C/S1 bZIP Network: A Regulatory Hub Orchestrating Plant Energy Homeostasis

Abstract

Sustaining energy homeostasis is crucial to every living being. To balance energy supply and demand, plants make use of an evolutionarily conserved management system consisting of two counteracting kinases, TOR (TARGET OF RAPAMYCIN) and SnRK1 (Snf1-RELATED PROTEIN KINASE 1). SnRK1 is involved in reorganizing enzymatic and transcriptional responses to survive energy-limiting conditions. Recently, members of the bZIP (basic leucine zipper) transcription factor family have been established as SnRK1 downstream mediators. We review here current knowledge on the functional impact of these group C and S₁ bZIPs, and analyze their regulation by environmental and endogenous cues. Given their specific homo- and heterodimerization, the so-called C/S₁ bZIP network is proposed to act as a signaling hub that coordinates plant development and stress responses.

Keywords: SnRK1 kinase; bZIP transcription factors; low-energy signaling.