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Editorial
. 2018 Aug:198:1-5.
doi: 10.1016/j.schres.2018.02.042. Epub 2018 Mar 7.

Sensorimotor gating deficits in schizophrenia: Advancing our understanding of the phenotype, its neural circuitry and genetic substrates

Affiliations
Editorial

Sensorimotor gating deficits in schizophrenia: Advancing our understanding of the phenotype, its neural circuitry and genetic substrates

Neal R Swerdlow et al. Schizophr Res. 2018 Aug.
No abstract available

Keywords: Antipsychotic; Genetics; Prepulse inhibition; Schizophrenia; Sensorimotor gating; Startle reflex.

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Conflict of interest statement

Conflict of interest: Dr. Light has received consulting compensation from Astellas, Boehringer Ingelheim, Merck, Lundbeck, Neuroverse, NeuroSig and Takeda. Dr. Swerdlow reports no consulting compensation.

References

    1. Abel KM, Allin MP, Hemsley DR, Geyer MA. Low dose ketamine increases prepulse inhibition in healthy men. Neuropharmacology. 2003;44(6):729–737. - PubMed
    1. Ahmari SE, Risbrough VB, Geyer MA, Simpson HB. Impaired sensorimotor gating in unmedicated adults with obsessive-compulsive disorder. Neuropsychopharmacology. 2012;37(5):1216–1223. - PMC - PubMed
    1. Baldan LC, Williams KA, Gallezot JD, Pogorelov V, Rapanelli M, Crowley M, Anderson GM, Loring E, Gorczyca R, Billingslea E, Wasylink S, Panza KE, Ercan-Sencicek AG, Krusong K, Leventhal BL, Ohtsu H, Bloch MH, Hughes ZA, Krystal JH, Maye L, de Araujo I, Ding YS, State MW, Pittenger C. Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice. Neuron. 2014;81(1):77–90. - PMC - PubMed
    1. Barrett SL, Kelly C, Watson DR, Bell R, King DJ. Normal levels of prepulse inhibition in the euthymic phase of bipolar disorder. Psychol Med. 2005;35(12):1737–1746. - PubMed
    1. Braff D, Stone C, Callaway E, Geyer M, Glick I, Bali L. Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology. 1978;15(4):339–343. - PubMed

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