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. 2018;30(1):9.
doi: 10.1186/s12302-018-0134-4. Epub 2018 Feb 27.

Short-chain perfluoroalkyl acids: environmental concerns and a regulatory strategy under REACH

Stephan Brendel  1 , Éva Fetter  1 , Claudia Staude  1 , Lena Vierke  1 , Annegret Biegel-Engler  1
Affiliations

Short-chain perfluoroalkyl acids: environmental concerns and a regulatory strategy under REACH

Stephan Brendel et al. Environ Sci Eur. 2018.

Abstract

Background: Short-chain PFASs (per- and polyfluoroalkyl substances) are widely used as alternatives to long-chain PFASs. Long-chain PFASs become gradually regulated under REACH (EC No. 1907/2006) and other international regulations, due to having persistent, bioaccumulative and toxic properties and/or being toxic for reproduction. The increasingly used short-chain PFASs are assumed to have a lower bioaccumulation potential. Nonetheless, they have other properties of concern and are already widely distributed in the environment, also in remote regions. The REACH Regulation does not directly address these emerging properties of concern, complicating the implementation of regulatory measures. Therefore, this study illustrates these environmental concerns and provides a strategy for a regulation of short-chain PFASs within REACH.

Results: Short-chain PFASs have a high mobility in soil and water, and final degradation products are extremely persistent. This results in a fast distribution to water resources, and consequently, also to a contamination of drinking water resources. Once emitted, short-chain PFASs remain in the environment. A lack of appropriate water treatment technologies results in everlasting background concentrations in the environment, and thus, organisms are permanently and poorly reversibly exposed. Considering such permanent exposure, it is very difficult to estimate long-term adverse effects in organisms. Short-chain PFASs enrich in edible parts of plants and the accumulation in food chains is unknown. Regarding these concerns and uncertainties, especially with respect to the precautionary principle, short-chain PFASs are of equivalent concern to PBT substances. Therefore, they should be identified as substances of very high concern (SVHC) under REACH. The SVHC identification should be followed by a restriction under REACH, which is the most efficient way to minimize the environmental and human exposure of short-chain PFASs in the European Union.

Conclusion: Due to an increasing use of short-chain PFASs, an effective regulation is urgently needed. The concerns of short-chain PFASs do not match the "classical" concerns as defined under REACH, but are not of minor concern. Therefore, it is of advantage to clearly define the concerns of short-chain PFASs. This might facilitate the following restriction process under REACH.

Keywords: Candidate list; PFAAs; PFASs; Per- and polyfluoroalkyl substances; REACH; Regulation; Restriction; SVHC.

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Figures

Fig. 1
Fig. 1
Terminology of per- and polyfluoroalkyl substances
Fig. 2
Fig. 2
Concerning properties of short-chain PFASs and a possible risk management strategy under REACH
See this image and copyright information in PMC

References

    1. Kirsch P. Modern fluoroorganic chemistry: synthesis, reactivity, applications. Hoboken: Wiley; 2013.
    1. Siegemund G, Schwertfeger W, Feiring A, Smart B, Behr F, Vogel H, McKusick B, Kirsch P. Fluorine compounds, organic. Ullmann’s encyclopedia of industrial chemistry. Weinheim: Wiley-VCH Verlag GmbH & Co. KGaA; 2000.
    1. Buck RC, Franklin J, Berger U, Conder JM, Cousins IT, De Voogt P, Jensen AA, Kannan K, Mabury SA, van Leeuwen SP. Perfluoroalkyl and polyfluoroalkyl substances in the environment: terminology, classification, and origins. Integr Environ Assess Manag. 2011;7:513–541. doi: 10.1002/ieam.258. - DOI - PMC - PubMed
    1. Swedish Chemicals Agency (2015) Occurrence and use of highly fluorinated substances and alternatives. www.kemi.se/en/global/rapporter/2015/report-7-15-occurrence-and-use-of-h.... Accessed 15 Jan 2018
    1. Gremmel C, Frömel T, Knepper TP. Systematic determination of perfluoroalkyl and polyfluoroalkyl substances (PFASs) in outdoor jackets. Chemosphere. 2016;160:173–180. doi: 10.1016/j.chemosphere.2016.06.043. - DOI - PubMed